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Re: xodcode post# 332739

Wednesday, 10/13/2021 10:19:51 AM

Wednesday, October 13, 2021 10:19:51 AM

Post# of 458030

"ANAVEX®2-73 activates the sigma-1 receptor (SIGMAR1). Data suggests that activation of SIGMAR1 results in the restoration of complete housekeeping function within the body and is pivotal to restoring neural cell homeostasis and promoting neuroplasticity. [1]

PET scan data previously confirmed dose-dependent target engagement of SIGMAR1 with ANAVEX®2-73. [2]"

My emphasis. Until the bolded wording becomes "Data confirms", we are going nowhere. Trying to get the FDA to accept Anavex's interpretation of the various third party studies that "suggest" the drug has merit, is what the whole thing is about and why there are no NDA's. Until then....

IMHO
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